BDBM50429741 CHEMBL1165106

SMILES: Cc1ccc(NC(=O)\C=C\c2ccc(O)c(O)c2)cc1

InChI Key: InChIKey=LAIQRLYWSPLUFU-WEVVVXLNSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50429741 (CHEMBL1165106) Show SMILES Cc1ccc(NC(=O)\C=C\c2ccc(O)c(O)c2)cc1 Show InChI InChI=1S/C16H15NO3/c1-11-2-6-13(7-3-11)17-16(20)9-5-12-4-8-14(18)15(19)10-12/h2-10,18-19H,1H3,(H,17,20)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 mins				Bioorg Med Chem Lett 23: 1206-11 (2013) Article DOI: 10.1016/j.bmcl.2013.01.027 BindingDB Entry DOI: 10.7270/Q2H996JF
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50429741 (CHEMBL1165106) Show SMILES Cc1ccc(NC(=O)\C=C\c2ccc(O)c(O)c2)cc1 Show InChI InChI=1S/C16H15NO3/c1-11-2-6-13(7-3-11)17-16(20)9-5-12-4-8-14(18)15(19)10-12/h2-10,18-19H,1H3,(H,17,20)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP1 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 mins				Bioorg Med Chem Lett 23: 1206-11 (2013) Article DOI: 10.1016/j.bmcl.2013.01.027 BindingDB Entry DOI: 10.7270/Q2H996JF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50429741 (CHEMBL1165106) Show SMILES Cc1ccc(NC(=O)\C=C\c2ccc(O)c(O)c2)cc1 Show InChI InChI=1S/C16H15NO3/c1-11-2-6-13(7-3-11)17-16(20)9-5-12-4-8-14(18)15(19)10-12/h2-10,18-19H,1H3,(H,17,20)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 mins				Bioorg Med Chem Lett 23: 1206-11 (2013) Article DOI: 10.1016/j.bmcl.2013.01.027 BindingDB Entry DOI: 10.7270/Q2H996JF
					More data for this Ligand-Target Pair