BDBM50430151 CHEMBL2338259

SMILES: O[C@]12CC3CC(C1)[C@@H](C(C3)C2)N1CCCc2c(cnn2C2CCCCC2)C1=O

InChI Key: InChIKey=PUMIFTMDJZBAFO-HAKKTOSCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50430151 (CHEMBL2338259) Show SMILES O[C@]12CC3CC(C1)[C@@H](C(C3)C2)N1CCCc2c(cnn2C2CCCCC2)C1=O |r,wU:7.13,1.0,TLB:9:8:2.3.4:6,THB:9:3:6:10.8.7,7:8:2:4.5.6,7:5:2:10.9.8,11:7:2.3.4:6,(38.01,-19.48,;36.48,-19.5,;37.69,-20.76,;36.18,-20.36,;36.17,-18.77,;35.12,-17.54,;36.47,-18.01,;33.73,-18.13,;33.76,-19.66,;34.78,-20.93,;35.15,-20,;32.55,-17.14,;32.92,-15.65,;31.99,-14.42,;30.46,-14.38,;29.47,-15.56,;29.77,-17.08,;28.43,-17.83,;27.29,-16.79,;27.93,-15.39,;27.17,-14.05,;27.96,-12.73,;27.2,-11.39,;25.66,-11.37,;24.88,-12.7,;25.63,-14.04,;31.15,-17.77,;31.11,-19.32,)| Show InChI InChI=1S/C23H33N3O2/c27-22-19-14-24-26(18-5-2-1-3-6-18)20(19)7-4-8-25(22)21-16-9-15-10-17(21)13-23(28,11-15)12-16/h14-18,21,28H,1-13H2/t15?,16?,17?,21-,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assay				Bioorg Med Chem Lett 23: 1617-21 (2013) Article DOI: 10.1016/j.bmcl.2013.01.090 BindingDB Entry DOI: 10.7270/Q27P90RZ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50430151 (CHEMBL2338259) Show SMILES O[C@]12CC3CC(C1)[C@@H](C(C3)C2)N1CCCc2c(cnn2C2CCCCC2)C1=O |r,wU:7.13,1.0,TLB:9:8:2.3.4:6,THB:9:3:6:10.8.7,7:8:2:4.5.6,7:5:2:10.9.8,11:7:2.3.4:6,(38.01,-19.48,;36.48,-19.5,;37.69,-20.76,;36.18,-20.36,;36.17,-18.77,;35.12,-17.54,;36.47,-18.01,;33.73,-18.13,;33.76,-19.66,;34.78,-20.93,;35.15,-20,;32.55,-17.14,;32.92,-15.65,;31.99,-14.42,;30.46,-14.38,;29.47,-15.56,;29.77,-17.08,;28.43,-17.83,;27.29,-16.79,;27.93,-15.39,;27.17,-14.05,;27.96,-12.73,;27.2,-11.39,;25.66,-11.37,;24.88,-12.7,;25.63,-14.04,;31.15,-17.77,;31.11,-19.32,)| Show InChI InChI=1S/C23H33N3O2/c27-22-19-14-24-26(18-5-2-1-3-6-18)20(19)7-4-8-25(22)21-16-9-15-10-17(21)13-23(28,11-15)12-16/h14-18,21,28H,1-13H2/t15?,16?,17?,21-,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assay				Bioorg Med Chem Lett 23: 1617-21 (2013) Article DOI: 10.1016/j.bmcl.2013.01.090 BindingDB Entry DOI: 10.7270/Q27P90RZ
					More data for this Ligand-Target Pair