BDBM50430154 CHEMBL2338256

SMILES: Cn1ncc2c1CCCN([C@H]1C3CC4CC1C[C@@](O)(C4)C3)C2=O

InChI Key: InChIKey=PMAPWQRZSCAYLV-SZBIMSGQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50430154 (CHEMBL2338256) Show SMILES Cn1ncc2c1CCCN([C@H]1C3CC4CC1C[C@@](O)(C4)C3)C2=O |r,wU:10.10,17.19,TLB:14:13:20:16.15.10,14:15:19.13.12:20,10:11:19:16.14.15,THB:10:15:19:12.11.20,9:10:19.13.12:20,(7.61,-4.19,;8.37,-5.53,;7.73,-6.94,;8.87,-7.98,;10.21,-7.22,;9.91,-5.71,;10.9,-4.53,;12.43,-4.57,;13.37,-5.8,;12.99,-7.29,;14.17,-8.28,;15.56,-7.69,;16.61,-8.92,;16.62,-10.5,;15.22,-11.08,;14.2,-9.81,;15.6,-10.14,;16.92,-9.64,;18.45,-9.62,;18.13,-10.91,;16.92,-8.16,;11.59,-7.92,;11.55,-9.46,)| Show InChI InChI=1S/C18H25N3O2/c1-20-15-3-2-4-21(17(22)14(15)10-19-20)16-12-5-11-6-13(16)9-18(23,7-11)8-12/h10-13,16,23H,2-9H2,1H3/t11?,12?,13?,16-,18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assay				Bioorg Med Chem Lett 23: 1617-21 (2013) Article DOI: 10.1016/j.bmcl.2013.01.090 BindingDB Entry DOI: 10.7270/Q27P90RZ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50430154 (CHEMBL2338256) Show SMILES Cn1ncc2c1CCCN([C@H]1C3CC4CC1C[C@@](O)(C4)C3)C2=O |r,wU:10.10,17.19,TLB:14:13:20:16.15.10,14:15:19.13.12:20,10:11:19:16.14.15,THB:10:15:19:12.11.20,9:10:19.13.12:20,(7.61,-4.19,;8.37,-5.53,;7.73,-6.94,;8.87,-7.98,;10.21,-7.22,;9.91,-5.71,;10.9,-4.53,;12.43,-4.57,;13.37,-5.8,;12.99,-7.29,;14.17,-8.28,;15.56,-7.69,;16.61,-8.92,;16.62,-10.5,;15.22,-11.08,;14.2,-9.81,;15.6,-10.14,;16.92,-9.64,;18.45,-9.62,;18.13,-10.91,;16.92,-8.16,;11.59,-7.92,;11.55,-9.46,)| Show InChI InChI=1S/C18H25N3O2/c1-20-15-3-2-4-21(17(22)14(15)10-19-20)16-12-5-11-6-13(16)9-18(23,7-11)8-12/h10-13,16,23H,2-9H2,1H3/t11?,12?,13?,16-,18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assay				Bioorg Med Chem Lett 23: 1617-21 (2013) Article DOI: 10.1016/j.bmcl.2013.01.090 BindingDB Entry DOI: 10.7270/Q27P90RZ
					More data for this Ligand-Target Pair