BDBM50430443 CHEMBL2334723

SMILES: Clc1ccc(cc1Cl)-c1nc2ccccc2n1-c1ccnc(NC2CCOCC2)n1

InChI Key: InChIKey=NUBHHICZZNJVSS-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430443 (CHEMBL2334723) Show SMILES Clc1ccc(cc1Cl)-c1nc2ccccc2n1-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C22H19Cl2N5O/c23-16-6-5-14(13-17(16)24)21-27-18-3-1-2-4-19(18)29(21)20-7-10-25-22(28-20)26-15-8-11-30-12-9-15/h1-7,10,13,15H,8-9,11-12H2,(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6X-tagged human recombinant JNK3 catalytic domain expressed in Escherichia coli BL21 (DE3) by surface plasmon reson...				Bioorg Med Chem 21: 2271-85 (2013) Article DOI: 10.1016/j.bmc.2013.02.021 BindingDB Entry DOI: 10.7270/Q29W0GVC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430443 (CHEMBL2334723) Show SMILES Clc1ccc(cc1Cl)-c1nc2ccccc2n1-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C22H19Cl2N5O/c23-16-6-5-14(13-17(16)24)21-27-18-3-1-2-4-19(18)29(21)20-7-10-25-22(28-20)26-15-8-11-30-12-9-15/h1-7,10,13,15H,8-9,11-12H2,(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP				Bioorg Med Chem Lett 23: 1639-42 (2013) Article DOI: 10.1016/j.bmcl.2013.01.082 BindingDB Entry DOI: 10.7270/Q2F76DXD
					More data for this Ligand-Target Pair