BDBM50430444 CHEMBL2334722

SMILES: COc1ccc2nc(-c3ccc4ccccc4c3)n(-c3ccnc(NC4CCCCC4)n3)c2c1

InChI Key: InChIKey=QJPWQJPSTPILRY-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430444 (CHEMBL2334722) Show SMILES COc1ccc2nc(-c3ccc4ccccc4c3)n(-c3ccnc(NC4CCCCC4)n3)c2c1 Show InChI InChI=1S/C28H27N5O/c1-34-23-13-14-24-25(18-23)33(26-15-16-29-28(32-26)30-22-9-3-2-4-10-22)27(31-24)21-12-11-19-7-5-6-8-20(19)17-21/h5-8,11-18,22H,2-4,9-10H2,1H3,(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6X-tagged human recombinant JNK3 catalytic domain expressed in Escherichia coli BL21 (DE3) by surface plasmon reson...				Bioorg Med Chem 21: 2271-85 (2013) Article DOI: 10.1016/j.bmc.2013.02.021 BindingDB Entry DOI: 10.7270/Q29W0GVC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430444 (CHEMBL2334722) Show SMILES COc1ccc2nc(-c3ccc4ccccc4c3)n(-c3ccnc(NC4CCCCC4)n3)c2c1 Show InChI InChI=1S/C28H27N5O/c1-34-23-13-14-24-25(18-23)33(26-15-16-29-28(32-26)30-22-9-3-2-4-10-22)27(31-24)21-12-11-19-7-5-6-8-20(19)17-21/h5-8,11-18,22H,2-4,9-10H2,1H3,(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP				Bioorg Med Chem Lett 23: 1639-42 (2013) Article DOI: 10.1016/j.bmcl.2013.01.082 BindingDB Entry DOI: 10.7270/Q2F76DXD
					More data for this Ligand-Target Pair