BDBM50430447 CHEMBL2334719

SMILES: C1CCC(CC1)Nc1nccc(n1)-n1c(nc2ccccc12)-c1ccc2ccccc2c1

InChI Key: InChIKey=YHHANOMLSREBSQ-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430447 (CHEMBL2334719) Show SMILES C1CCC(CC1)Nc1nccc(n1)-n1c(nc2ccccc12)-c1ccc2ccccc2c1 Show InChI InChI=1S/C27H25N5/c1-2-10-22(11-3-1)29-27-28-17-16-25(31-27)32-24-13-7-6-12-23(24)30-26(32)21-15-14-19-8-4-5-9-20(19)18-21/h4-9,12-18,22H,1-3,10-11H2,(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6X-tagged human recombinant JNK3 catalytic domain expressed in Escherichia coli BL21 (DE3) by surface plasmon reson...				Bioorg Med Chem 21: 2271-85 (2013) Article DOI: 10.1016/j.bmc.2013.02.021 BindingDB Entry DOI: 10.7270/Q29W0GVC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50430447 (CHEMBL2334719) Show SMILES C1CCC(CC1)Nc1nccc(n1)-n1c(nc2ccccc12)-c1ccc2ccccc2c1 Show InChI InChI=1S/C27H25N5/c1-2-10-22(11-3-1)29-27-28-17-16-25(31-27)32-24-13-7-6-12-23(24)30-26(32)21-15-14-19-8-4-5-9-20(19)18-21/h4-9,12-18,22H,1-3,10-11H2,(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Binding affinity to JNK3 (unknown origin) by surface plasmon resonance analysis in presence of ATP				Bioorg Med Chem Lett 23: 1639-42 (2013) Article DOI: 10.1016/j.bmcl.2013.01.082 BindingDB Entry DOI: 10.7270/Q2F76DXD
					More data for this Ligand-Target Pair