BDBM50431900 CHEMBL2347815

SMILES: CS(=O)(=O)c1ccc(cc1)-c1ccc2c(c(cnc2c1)C#N)-n1ccnc1

InChI Key: InChIKey=QPLVDTOZGCQPEP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50431900 (CHEMBL2347815) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(c(cnc2c1)C#N)-n1ccnc1 Show InChI InChI=1S/C20H14N4O2S/c1-27(25,26)17-5-2-14(3-6-17)15-4-7-18-19(10-15)23-12-16(11-21)20(18)24-9-8-22-13-24/h2-10,12-13H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	682	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of wild type GST-tagged LRRK2 (970-2527 amino acids)(unknown origin) assessed as inhibition of LRRKtide phosphorylation by HTRF assay				Bioorg Med Chem Lett 23: 1974-7 (2013) Article DOI: 10.1016/j.bmcl.2013.02.041 BindingDB Entry DOI: 10.7270/Q2FQ9XZ1
					More data for this Ligand-Target Pair