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BDBM50432457 CHEMBL2349301

SMILES: CC(C)C[C@H](CCO)Nc1nc(SCc2ccccc2Cl)nc2nc(N)sc12

InChI Key: InChIKey=GWJWFBDTQOANAA-ZDUSSCGKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432457   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X3-C chemokine receptor 1


(Homo sapiens (Human))		BDBM50432457
PNG
(CHEMBL2349301)
Show SMILES CC(C)C[C@H](CCO)Nc1nc(SCc2ccccc2Cl)nc2nc(N)sc12 |r|
Show InChI InChI=1S/C19H24ClN5OS2/c1-11(2)9-13(7-8-26)22-16-15-17(23-18(21)28-15)25-19(24-16)27-10-12-5-3-4-6-14(12)20/h3-6,11,13,26H,7-10H2,1-2H3,(H3,21,22,23,24,25)/t13-/m0/s1
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Similars
Article
PubMed
 91n/an/an/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis

J Med Chem 56: 3177-90 (2013)


Article DOI: 10.1021/jm3012273
BindingDB Entry DOI: 10.7270/Q2ST7R7X
More data for this
Ligand-Target Pair