null

SMILES: C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1nccs1

InChI Key: InChIKey=BNOKIFBZSXYOCT-JTQLQIEISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50432780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50432780 (CHEMBL2348806) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1nccs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-15-4-2-3-12(20)16(15)21)17(25)23-11-5-6-14-13(9-11)24-18(27-14)19-22-7-8-28-19/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of human IMPDH2				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432780 (CHEMBL2348806) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1nccs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-15-4-2-3-12(20)16(15)21)17(25)23-11-5-6-14-13(9-11)24-18(27-14)19-22-7-8-28-19/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432780 (CHEMBL2348806) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1nccs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-15-4-2-3-12(20)16(15)21)17(25)23-11-5-6-14-13(9-11)24-18(27-14)19-22-7-8-28-19/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair