BDBM50432895 CHEMBL2376835

SMILES: Nn1c(SCc2cccc(c2)[N+]([O-])=O)nnc1-c1c[nH]c2ccccc12

InChI Key: InChIKey=VHXJPGHMGIVOQD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50432895 (CHEMBL2376835) Show SMILES Nn1c(SCc2cccc(c2)[N+]([O-])=O)nnc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C17H14N6O2S/c18-22-16(14-9-19-15-7-2-1-6-13(14)15)20-21-17(22)26-10-11-4-3-5-12(8-11)23(24)25/h1-9,19H,10,18H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Competitive binding affinity to his-tagged Bcl-2 (unknown origin) after 1 hr by ELISA in presence of Bim peptide				Bioorg Med Chem Lett 23: 2391-4 (2013) Article DOI: 10.1016/j.bmcl.2013.02.029 BindingDB Entry DOI: 10.7270/Q2PZ5B66
					More data for this Ligand-Target Pair