BDBM50433399 CHEMBL2375608

SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1

InChI Key: InChIKey=VERDULHGTFVKHY-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50433399 (CHEMBL2375608) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C25H24N4O2S/c1-19-9-11-20(12-10-19)32(30,31)29-16-14-28(15-17-29)25-18-24(23-8-4-5-13-26-23)27-22-7-3-2-6-21(22)25/h2-13,18H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50433399 (CHEMBL2375608) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C25H24N4O2S/c1-19-9-11-20(12-10-19)32(30,31)29-16-14-28(15-17-29)25-18-24(23-8-4-5-13-26-23)27-22-7-3-2-6-21(22)25/h2-13,18H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 2 in presence of Mn2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50433399 (CHEMBL2375608) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C25H24N4O2S/c1-19-9-11-20(12-10-19)32(30,31)29-16-14-28(15-17-29)25-18-24(23-8-4-5-13-26-23)27-22-7-3-2-6-21(22)25/h2-13,18H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Mn2+				J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z
					More data for this Ligand-Target Pair