BDBM50434237 CHEMBL2385743

SMILES: CCOc1cc(ccc1OCc1ccccc1Cl)C1NC(=O)N=C(C)C1C(C)=O

InChI Key: InChIKey=VJHNXBIMUUPOLB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-alpha (Homo sapiens (Human))	BDBM50434237 (CHEMBL2385743) Show SMILES CCOc1cc(ccc1OCc1ccccc1Cl)C1NC(=O)N=C(C)C1C(C)=O |t:24| Show InChI InChI=1S/C22H23ClN2O4/c1-4-28-19-11-15(21-20(14(3)26)13(2)24-22(27)25-21)9-10-18(19)29-12-16-7-5-6-8-17(16)23/h5-11,20-21H,4,12H2,1-3H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a
Genfit SA Curated by ChEMBL					Assay Description Partial agonist activity at GST-fussed RORalpha (unknown origin) assessed as recruitment of TIF2-BAP protein after overnight incubation by pull down ...				ACS Med Chem Lett 4: 504-8 (2013) Article DOI: 10.1021/ml300471d BindingDB Entry DOI: 10.7270/Q22R3T1B
					More data for this Ligand-Target Pair