BDBM50434466 CHEMBL2385117

SMILES: OC(=O)Cc1cn(nc1-c1ccncc1)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=ZIVCNQCTWXONIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50434466 (CHEMBL2385117) Show SMILES OC(=O)Cc1cn(nc1-c1ccncc1)C(c1ccc(F)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C23H17F2N3O2/c24-19-5-1-16(2-6-19)23(17-3-7-20(25)8-4-17)28-14-18(13-21(29)30)22(27-28)15-9-11-26-12-10-15/h1-12,14,23H,13H2,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding preinc...				Bioorg Med Chem Lett 23: 3349-53 (2013) Article DOI: 10.1016/j.bmcl.2013.03.093 BindingDB Entry DOI: 10.7270/Q2C24XSQ
					More data for this Ligand-Target Pair