BDBM50434543 CHEMBL2386178

SMILES: Cc1ccccc1[B-]1([NH2+]CCO1)c1ccccc1

InChI Key: InChIKey=HJRVYUICOSHAEQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 6 (Homo sapiens (Human))	BDBM50434543 (CHEMBL2386178) Show SMILES Cc1ccccc1[B-]1([NH2+]CCO1)c1ccccc1 Show InChI InChI=1S/C15H18BNO/c1-13-7-5-6-10-15(13)16(17-11-12-18-16)14-8-3-2-4-9-14/h2-10H,11-12,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assay				Bioorg Med Chem 21: 3202-13 (2013) Article DOI: 10.1016/j.bmc.2013.03.037 BindingDB Entry DOI: 10.7270/Q2KK9D6T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 6 (Homo sapiens (Human))	BDBM50434543 (CHEMBL2386178) Show SMILES Cc1ccccc1[B-]1([NH2+]CCO1)c1ccccc1 Show InChI InChI=1S/C15H18BNO/c1-13-7-5-6-10-15(13)16(17-11-12-18-16)14-8-3-2-4-9-14/h2-10H,11-12,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assay				Bioorg Med Chem 21: 3202-13 (2013) Article DOI: 10.1016/j.bmc.2013.03.037 BindingDB Entry DOI: 10.7270/Q2KK9D6T
					More data for this Ligand-Target Pair