BDBM50434702 CHEMBL2385192

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(C)cc5)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=ZYRMNEUJELXMAA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50434702 (CHEMBL2385192) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(C)cc5)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C41H40FN5O5/c1-26-9-12-29(13-10-26)47-34-8-5-4-7-30(34)40(48)39(45-47)41(49)44-28-11-14-36(32(42)23-28)52-35-15-18-43-33-25-38(37(50-3)24-31(33)35)51-22-6-19-46-20-16-27(2)17-21-46/h4-5,7-15,18,23-25,27H,6,16-17,19-22H2,1-3H3,(H,44,49)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 21: 2843-55 (2013) Article DOI: 10.1016/j.bmc.2013.04.013 BindingDB Entry DOI: 10.7270/Q25D8T6Z
					More data for this Ligand-Target Pair