BDBM50434703 CHEMBL2385187

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(C)cc5C)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=ANIOMFIDASIHRC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50434703 (CHEMBL2385187) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(C)cc5C)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C41H40FN5O5/c1-26-12-14-33(27(2)22-26)47-34-11-6-5-10-29(34)40(48)39(45-47)41(49)44-28-13-15-36(31(42)23-28)52-35-16-17-43-32-25-38(37(50-3)24-30(32)35)51-21-9-20-46-18-7-4-8-19-46/h5-6,10-17,22-25H,4,7-9,18-21H2,1-3H3,(H,44,49)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 21: 2843-55 (2013) Article DOI: 10.1016/j.bmc.2013.04.013 BindingDB Entry DOI: 10.7270/Q25D8T6Z
					More data for this Ligand-Target Pair