BDBM50434717 CHEMBL2385199

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cc(ccc5Cl)C(F)(F)F)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=JYQLVVOBTMGKEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50434717 (CHEMBL2385199) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cc(ccc5Cl)C(F)(F)F)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C39H32ClF4N5O5/c1-52-34-21-26-29(22-35(34)53-18-6-17-48-15-4-5-16-48)45-14-13-32(26)54-33-12-10-24(20-28(33)41)46-38(51)36-37(50)25-7-2-3-8-30(25)49(47-36)31-19-23(39(42,43)44)9-11-27(31)40/h2-3,7-14,19-22H,4-6,15-18H2,1H3,(H,46,51)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 21: 2843-55 (2013) Article DOI: 10.1016/j.bmc.2013.04.013 BindingDB Entry DOI: 10.7270/Q25D8T6Z
					More data for this Ligand-Target Pair