BDBM50435147 CHEMBL2392728

SMILES: O=C(Nc1nnc(o1)-c1cccs1)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=KHVOWDVVVDBYMB-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50435147 (CHEMBL2392728) Show SMILES O=C(Nc1nnc(o1)-c1cccs1)NC12CC3CC(CC(C3)C1)C2 |TLB:13:14:17:21.20.19,THB:15:16:19:23.14.22,15:14:17.16.21:19,22:14:17:21.20.19,22:20:17:23.15.14| Show InChI InChI=1S/C17H20N4O2S/c22-15(18-16-21-20-14(23-16)13-2-1-3-24-13)19-17-7-10-4-11(8-17)6-12(5-10)9-17/h1-3,10-12H,4-9H2,(H2,18,19,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins before substrate addition measured after 1...				Bioorg Med Chem 21: 2587-99 (2013) Article DOI: 10.1016/j.bmc.2013.02.028 BindingDB Entry DOI: 10.7270/Q2DR2WXJ
					More data for this Ligand-Target Pair