null

SMILES: F[C@H]1CNCC[C@H]1n1nnc2cnc3[nH]ccc3c12

InChI Key: InChIKey=BIWCELRLKBXHKJ-WCBMZHEXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50435514 (CHEMBL2392496) Show SMILES F[C@H]1CNCC[C@H]1n1nnc2cnc3[nH]ccc3c12 |r| Show InChI InChI=1S/C12H13FN6/c13-8-5-14-3-2-10(8)19-11-7-1-4-15-12(7)16-6-9(11)17-18-19/h1,4,6,8,10,14H,2-3,5H2,(H,15,16)/t8-,10+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Bioorg Med Chem Lett 23: 3592-8 (2013) Article DOI: 10.1016/j.bmcl.2013.04.018 BindingDB Entry DOI: 10.7270/Q2GH9KB2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50435514 (CHEMBL2392496) Show SMILES F[C@H]1CNCC[C@H]1n1nnc2cnc3[nH]ccc3c12 |r| Show InChI InChI=1S/C12H13FN6/c13-8-5-14-3-2-10(8)19-11-7-1-4-15-12(7)16-6-9(11)17-18-19/h1,4,6,8,10,14H,2-3,5H2,(H,15,16)/t8-,10+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	446	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Bioorg Med Chem Lett 23: 3592-8 (2013) Article DOI: 10.1016/j.bmcl.2013.04.018 BindingDB Entry DOI: 10.7270/Q2GH9KB2
					More data for this Ligand-Target Pair