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SMILES: Cc1cc(Cc2cccc(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2cccccc12

InChI Key: InChIKey=RGUZWHGCTAFVDA-SJSRKZJXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436117   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50436117
PNG
(CHEMBL2397443)
Show SMILES Cc1cc(Cc2cccc(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2cccccc12 |r|
Show InChI InChI=1S/C24H26O5/c1-14-10-17(19-9-4-2-3-8-18(14)19)12-15-6-5-7-16(11-15)24-23(28)22(27)21(26)20(13-25)29-24/h2-11,20-28H,12-13H2,1H3/t20-,21-,22+,23-,24+/m1/s1
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Article
PubMed
n/an/a 4.40E+4n/an/an/an/an/an/a



Astellas Pharmaceutical Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation

Bioorg Med Chem 21: 3934-48 (2013)


Article DOI: 10.1016/j.bmc.2013.03.067
BindingDB Entry DOI: 10.7270/Q2ZC848C
More data for this
Ligand-Target Pair