BDBM50436659 CHEMBL2398264

SMILES: OC(=O)c1cccc(n1)-c1cccc2C(CCc12)=NNc1nc2ccccc2s1

InChI Key: InChIKey=RUVNKPIUFSPOIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50436659 (CHEMBL2398264) Show SMILES OC(=O)c1cccc(n1)-c1cccc2C(CCc12)=NNc1nc2ccccc2s1 |w:18.21| Show InChI InChI=1S/C22H16N4O2S/c27-21(28)19-9-4-8-16(23-19)14-5-3-6-15-13(14)11-12-17(15)25-26-22-24-18-7-1-2-10-20(18)29-22/h1-10H,11-12H2,(H,24,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute of Medical Research Curated by ChEMBL					Assay Description Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assay				J Med Chem 56: 5514-40 (2014) Article DOI: 10.1021/jm400556w BindingDB Entry DOI: 10.7270/Q2X92CQT
					More data for this Ligand-Target Pair