BDBM50436665 CHEMBL2398265

SMILES: CC(N=Nc1nc2ccccc2s1)c1ccc(o1)-c1cccc(C(O)=O)c1C

InChI Key: InChIKey=OIEGXMMZWNRSBO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50436665 (CHEMBL2398265) Show SMILES CC(N=Nc1nc2ccccc2s1)c1ccc(o1)-c1cccc(C(O)=O)c1C |w:3.3| Show InChI InChI=1S/C21H17N3O3S/c1-12-14(6-5-7-15(12)20(25)26)18-11-10-17(27-18)13(2)23-24-21-22-16-8-3-4-9-19(16)28-21/h3-11,13H,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute of Medical Research Curated by ChEMBL					Assay Description Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assay				J Med Chem 56: 5514-40 (2014) Article DOI: 10.1021/jm400556w BindingDB Entry DOI: 10.7270/Q2X92CQT
					More data for this Ligand-Target Pair