BDBM50436671 CHEMBL2398256

SMILES: CC1(C)CC(=NNc2nc3ccccc3s2)c2cc(ccc2O1)-c1cccc(n1)C(O)=O

InChI Key: InChIKey=BFRNOQMQSFEEOO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50436671 (CHEMBL2398256) Show SMILES CC1(C)CC(=NNc2nc3ccccc3s2)c2cc(ccc2O1)-c1cccc(n1)C(O)=O |w:5.5| Show InChI InChI=1S/C24H20N4O3S/c1-24(2)13-19(27-28-23-26-17-6-3-4-9-21(17)32-23)15-12-14(10-11-20(15)31-24)16-7-5-8-18(25-16)22(29)30/h3-12H,13H2,1-2H3,(H,26,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute of Medical Research Curated by ChEMBL					Assay Description Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assay				J Med Chem 56: 5514-40 (2014) Article DOI: 10.1021/jm400556w BindingDB Entry DOI: 10.7270/Q2X92CQT
					More data for this Ligand-Target Pair