BDBM50436928 CHEMBL2402153

SMILES: Clc1ccc(s1)S(=O)(=O)NC(=O)N1CCN(CC1)c1ncc(cc1Cl)C(=O)C1CC1

InChI Key: InChIKey=VEJNOPYLXFLQPA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50436928 (CHEMBL2402153) Show SMILES Clc1ccc(s1)S(=O)(=O)NC(=O)N1CCN(CC1)c1ncc(cc1Cl)C(=O)C1CC1 Show InChI InChI=1S/C18H18Cl2N4O4S2/c19-13-9-12(16(25)11-1-2-11)10-21-17(13)23-5-7-24(8-6-23)18(26)22-30(27,28)15-4-3-14(20)29-15/h3-4,9-11H,1-2,5-8H2,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregation				Eur J Med Chem 65: 360-75 (2013) Article DOI: 10.1016/j.ejmech.2013.04.007 BindingDB Entry DOI: 10.7270/Q2PK0HJ2
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50436928 (CHEMBL2402153) Show SMILES Clc1ccc(s1)S(=O)(=O)NC(=O)N1CCN(CC1)c1ncc(cc1Cl)C(=O)C1CC1 Show InChI InChI=1S/C18H18Cl2N4O4S2/c19-13-9-12(16(25)11-1-2-11)10-21-17(13)23-5-7-24(8-6-23)18(26)22-30(27,28)15-4-3-14(20)29-15/h3-4,9-11H,1-2,5-8H2,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysis				Eur J Med Chem 65: 360-75 (2013) Article DOI: 10.1016/j.ejmech.2013.04.007 BindingDB Entry DOI: 10.7270/Q2PK0HJ2
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50436928 (CHEMBL2402153) Show SMILES Clc1ccc(s1)S(=O)(=O)NC(=O)N1CCN(CC1)c1ncc(cc1Cl)C(=O)C1CC1 Show InChI InChI=1S/C18H18Cl2N4O4S2/c19-13-9-12(16(25)11-1-2-11)10-21-17(13)23-5-7-24(8-6-23)18(26)22-30(27,28)15-4-3-14(20)29-15/h3-4,9-11H,1-2,5-8H2,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysis				Eur J Med Chem 65: 360-75 (2013) Article DOI: 10.1016/j.ejmech.2013.04.007 BindingDB Entry DOI: 10.7270/Q2PK0HJ2
					More data for this Ligand-Target Pair