BDBM50437013 CHEMBL2402909
SMILES: CCNC(=O)C(C1CCN(CC1)c1ccc(NC(=O)c2c(C)noc2C)cc1F)c1ccccc1
InChI Key: InChIKey=GGILYYFFOHRFRB-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Neuropeptide Y receptor type 2 (Homo sapiens (Human)) | BDBM50437013![]() (CHEMBL2402909) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 476 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research& Development LLC Curated by ChEMBL | Assay Description Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysis | Bioorg Med Chem Lett 23: 4141-4 (2013) Article DOI: 10.1016/j.bmcl.2013.05.038 BindingDB Entry DOI: 10.7270/Q29C6ZV8 | |||||||||||
More data for this Ligand-Target Pair |