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BDBM50437019 CHEMBL2403063

SMILES: COc1cc(Nc2ncc(Cl)c(n2)-c2cccc(c2)C(O)=O)ccc1N1CCN(C)CC1

InChI Key: InChIKey=BNOUWVFOOUWOLD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437019   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
PAK 1/CDC42


(Homo sapiens (Human))		BDBM50437019
PNG
(CHEMBL2403063)
Show SMILES COc1cc(Nc2ncc(Cl)c(n2)-c2cccc(c2)C(O)=O)ccc1N1CCN(C)CC1
Show InChI InChI=1S/C23H24ClN5O3/c1-28-8-10-29(11-9-28)19-7-6-17(13-20(19)32-2)26-23-25-14-18(24)21(27-23)15-4-3-5-16(12-15)22(30)31/h3-7,12-14H,8-11H2,1-2H3,(H,30,31)(H,25,26,27)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.21E+3n/an/an/an/an/an/a



Astex Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PAK1 using MBP as substrate by scintillation counting analysis in presence of [gamma-32P]ATP

Bioorg Med Chem Lett 23: 4072-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.05.059
BindingDB Entry DOI: 10.7270/Q25M674B
More data for this
Ligand-Target Pair