BDBM50437311 CHEMBL2407464
SMILES: OC(=O)c1sc2cc(ccc2c1Cl)-n1c(n[nH]c1=S)-c1ccc(F)cc1
InChI Key: InChIKey=PNSKQUARDFXFAX-UHFFFAOYSA-N
Data: 1 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human)) | BDBM50437311 (CHEMBL2407464) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.70E+4 | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis... | ACS Med Chem Lett 4: 601-605 (2013) Article DOI: 10.1021/ml400032y BindingDB Entry DOI: 10.7270/Q22N53PW | |||||||||||
More data for this Ligand-Target Pair |