BDBM50437320 CHEMBL2407594

SMILES: Cc1ccc2c(Cl)c(sc2c1)-c1nnc(SCC(O)=O)n1-c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=VDZZRDXTYHRDRE-UHFFFAOYSA-N

Data: 1 Kd

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50437320 (CHEMBL2407594) Show SMILES Cc1ccc2c(Cl)c(sc2c1)-c1nnc(SCC(O)=O)n1-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H12Cl3N3O2S2/c1-9-2-4-11-14(6-9)29-17(16(11)22)18-23-24-19(28-8-15(26)27)25(18)10-3-5-12(20)13(21)7-10/h2-7H,8H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...				ACS Med Chem Lett 4: 601-605 (2013) Article DOI: 10.1021/ml400032y BindingDB Entry DOI: 10.7270/Q22N53PW
					More data for this Ligand-Target Pair