BDBM50437327 CHEMBL2023325

SMILES: Oc1c(CN2CCCCC2)cc(Cl)c2cccnc12

InChI Key: InChIKey=IEKUNQQLSAJNIG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50437327 (CHEMBL2023325) Show SMILES Oc1c(CN2CCCCC2)cc(Cl)c2cccnc12 Show InChI InChI=1S/C15H17ClN2O/c16-13-9-11(10-18-7-2-1-3-8-18)15(19)14-12(13)5-4-6-17-14/h4-6,9,19H,1-3,7-8,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 1				ACS Med Chem Lett 4: (2013) Article DOI: 10.1021/ml400034m BindingDB Entry DOI: 10.7270/Q2XW4M72
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50437327 (CHEMBL2023325) Show SMILES Oc1c(CN2CCCCC2)cc(Cl)c2cccnc12 Show InChI InChI=1S/C15H17ClN2O/c16-13-9-11(10-18-7-2-1-3-8-18)15(19)14-12(13)5-4-6-17-14/h4-6,9,19H,1-3,7-8,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of human methionine aminopeptidase 2				ACS Med Chem Lett 4: (2013) Article DOI: 10.1021/ml400034m BindingDB Entry DOI: 10.7270/Q2XW4M72
					More data for this Ligand-Target Pair