BDBM50438041 CHEMBL2409597

SMILES: COc1cc(Nc2nc(Cl)nc(Nc3cccc(NS(C)(=O)=O)c3)n2)cc(OC)c1OC

InChI Key: InChIKey=GUJIKSRSIMHNDC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50438041 (CHEMBL2409597) Show SMILES COc1cc(Nc2nc(Cl)nc(Nc3cccc(NS(C)(=O)=O)c3)n2)cc(OC)c1OC Show InChI InChI=1S/C19H21ClN6O5S/c1-29-14-9-13(10-15(30-2)16(14)31-3)22-19-24-17(20)23-18(25-19)21-11-6-5-7-12(8-11)26-32(4,27)28/h5-10,26H,1-4H3,(H2,21,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Descartes Curated by ChEMBL					Assay Description Inhibition of pre-activated recombinant full length FAK (unknown origin) using ULight labeled poly(Glu/Tyr) as substrate after 1.6 hrs by TR-FRET ass...				Bioorg Med Chem Lett 23: 4552-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.038 BindingDB Entry DOI: 10.7270/Q2GM88RC
					More data for this Ligand-Target Pair