BDBM50438050 CHEMBL2409590

SMILES: CNC(=O)c1ccccc1Nc1ncnc(Nc2cc(CCC(N)=O)c(OC)c(OC)c2)n1

InChI Key: InChIKey=LRBQVMYFUFNPGR-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50438050 (CHEMBL2409590) Show SMILES CNC(=O)c1ccccc1Nc1ncnc(Nc2cc(CCC(N)=O)c(OC)c(OC)c2)n1 Show InChI InChI=1S/C22H25N7O4/c1-24-20(31)15-6-4-5-7-16(15)28-22-26-12-25-21(29-22)27-14-10-13(8-9-18(23)30)19(33-3)17(11-14)32-2/h4-7,10-12H,8-9H2,1-3H3,(H2,23,30)(H,24,31)(H2,25,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Descartes Curated by ChEMBL					Assay Description Inhibition of pre-activated recombinant full length FAK (unknown origin) using ULight labeled poly(Glu/Tyr) as substrate after 1.6 hrs by TR-FRET ass...				Bioorg Med Chem Lett 23: 4552-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.038 BindingDB Entry DOI: 10.7270/Q2GM88RC
					More data for this Ligand-Target Pair