BDBM50438054 CHEMBL2409586

SMILES: COc1ccc(Nc2ncnc(Nc3ccccc3NS(C)(=O)=O)n2)c(OC)c1

InChI Key: InChIKey=NGSBOJHOSORDHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50438054 (CHEMBL2409586) Show SMILES COc1ccc(Nc2ncnc(Nc3ccccc3NS(C)(=O)=O)n2)c(OC)c1 Show InChI InChI=1S/C18H20N6O4S/c1-27-12-8-9-15(16(10-12)28-2)22-18-20-11-19-17(23-18)21-13-6-4-5-7-14(13)24-29(3,25)26/h4-11,24H,1-3H3,(H2,19,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Descartes Curated by ChEMBL					Assay Description Inhibition of pre-activated recombinant full length FAK (unknown origin) using ULight labeled poly(Glu/Tyr) as substrate after 1.6 hrs by TR-FRET ass...				Bioorg Med Chem Lett 23: 4552-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.038 BindingDB Entry DOI: 10.7270/Q2GM88RC
					More data for this Ligand-Target Pair