BDBM50438931 CHEMBL2420634

SMILES: O=C(NCc1ccc(cc1)S(=O)(=O)c1ccc(nc1)N1CCOCC1)c1cnc2nccn2c1

InChI Key: InChIKey=DXFBPTYMBKBYAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50438931 (CHEMBL2420634) Show SMILES O=C(NCc1ccc(cc1)S(=O)(=O)c1ccc(nc1)N1CCOCC1)c1cnc2nccn2c1 Show InChI InChI=1S/C23H22N6O4S/c30-22(18-14-27-23-24-7-8-29(23)16-18)26-13-17-1-3-19(4-2-17)34(31,32)20-5-6-21(25-15-20)28-9-11-33-12-10-28/h1-8,14-16H,9-13H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Forma Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged NAMPT (unknown origin) expressed in Escherichia coli BL21 using nicotinamide as substrate preincubated for 15 min...				J Med Chem 56: 6413-33 (2013) Article DOI: 10.1021/jm4008664 BindingDB Entry DOI: 10.7270/Q2H996MB
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