BDBM50439392 CHEMBL2420400

SMILES: COC(=O)c1c(NC(=O)CSc2ccc(cc2)[N+]([O-])=O)cnn1CCc1ccccc1

InChI Key: InChIKey=HRNHDIVPSSXCAR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor superfamily member 6 (Rattus norvegicus)	BDBM50439392 (CHEMBL2420400) Show SMILES COC(=O)c1c(NC(=O)CSc2ccc(cc2)[N+]([O-])=O)cnn1CCc1ccccc1 Show InChI InChI=1S/C21H20N4O5S/c1-30-21(27)20-18(13-22-24(20)12-11-15-5-3-2-4-6-15)23-19(26)14-31-17-9-7-16(8-10-17)25(28)29/h2-10,13H,11-12,14H2,1H3,(H,23,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	457	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Fas-mediated cell death in oxygen and glucose deprived rat H9c2 cells treated 30 mins before oxygen and glucose deprivation measured af...				Bioorg Med Chem Lett 23: 5155-64 (2013) Article DOI: 10.1016/j.bmcl.2013.07.018 BindingDB Entry DOI: 10.7270/Q2DB838N
					More data for this Ligand-Target Pair