BDBM50439477 CHEMBL2417903

SMILES: CCNc1ccc(c(n1)C(=O)Nc1ccc2c(N)nccc2c1)-c1ccc(cc1C(O)=O)C(=O)NCC(C)(C)C

InChI Key: InChIKey=DKSGJHUZOLTNAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII (Homo sapiens (Human))	BDBM50439477 (CHEMBL2417903) Show SMILES CCNc1ccc(c(n1)C(=O)Nc1ccc2c(N)nccc2c1)-c1ccc(cc1C(O)=O)C(=O)NCC(C)(C)C Show InChI InChI=1S/C30H32N6O4/c1-5-32-24-11-10-22(21-8-6-18(15-23(21)29(39)40)27(37)34-16-30(2,3)4)25(36-24)28(38)35-19-7-9-20-17(14-19)12-13-33-26(20)31/h6-15H,5,16H2,1-4H3,(H2,31,33)(H,32,36)(H,34,37)(H,35,38)(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 mins				Bioorg Med Chem Lett 23: 5239-43 (2013) Article DOI: 10.1016/j.bmcl.2013.06.028 BindingDB Entry DOI: 10.7270/Q2CC123C
					More data for this Ligand-Target Pair