BDBM50440537 CHEMBL2426173

SMILES: Cc1cc(NC(=O)Nc2nnc(s2)-c2ccncc2)ccc1-c1cn[nH]c1

InChI Key: InChIKey=PWMMEGBMFSUOKK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bloom syndrome protein (Homo sapiens (Human))	BDBM50440537 (CHEMBL2426173) Show SMILES Cc1cc(NC(=O)Nc2nnc(s2)-c2ccncc2)ccc1-c1cn[nH]c1 Show InChI InChI=1S/C18H15N7OS/c1-11-8-14(2-3-15(11)13-9-20-21-10-13)22-17(26)23-18-25-24-16(27-18)12-4-6-19-7-5-12/h2-10H,1H3,(H,20,21)(H2,22,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair