BDBM50441225 CHEMBL2431032

SMILES: ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(cc2)-c2ccccc2)cc1

InChI Key: InChIKey=LGTBURVEOHTXLS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50441225 (CHEMBL2431032) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C21H20N2O5S/c24-21(23-25)14-22-29(26,27)20-12-10-19(11-13-20)28-15-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-13,22,25H,14-15H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...				J Med Chem 56: 8089-103 (2013) Article DOI: 10.1021/jm4011753 BindingDB Entry DOI: 10.7270/Q2DR2WZ0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50441225 (CHEMBL2431032) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C21H20N2O5S/c24-21(23-25)14-22-29(26,27)20-12-10-19(11-13-20)28-15-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-13,22,25H,14-15H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...				J Med Chem 56: 8089-103 (2013) Article DOI: 10.1021/jm4011753 BindingDB Entry DOI: 10.7270/Q2DR2WZ0
					More data for this Ligand-Target Pair