BDBM50441226 CHEMBL2431031

SMILES: ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1

InChI Key: InChIKey=APPNLLFVKPQJGQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50441226 (CHEMBL2431031) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C16H15F3N2O6S/c17-16(18,19)27-13-3-1-11(2-4-13)10-26-12-5-7-14(8-6-12)28(24,25)20-9-15(22)21-23/h1-8,20,23H,9-10H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...				J Med Chem 56: 8089-103 (2013) Article DOI: 10.1021/jm4011753 BindingDB Entry DOI: 10.7270/Q2DR2WZ0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50441226 (CHEMBL2431031) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C16H15F3N2O6S/c17-16(18,19)27-13-3-1-11(2-4-13)10-26-12-5-7-14(8-6-12)28(24,25)20-9-15(22)21-23/h1-8,20,23H,9-10H2,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...				J Med Chem 56: 8089-103 (2013) Article DOI: 10.1021/jm4011753 BindingDB Entry DOI: 10.7270/Q2DR2WZ0
					More data for this Ligand-Target Pair