null
SMILES: Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc23)cc1Cl
InChI Key: InChIKey=RCCXKBNAOJAAHI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM50441435 (CHEMBL2436265) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Curated by ChEMBL | Assay Description Inhibition of HO-2 in Sprague-Dawley rat brain microsomal fractions assessed as carbon monoxide formation from methemalbumin after 10 mins by gas chr... | Bioorg Med Chem 21: 6788-95 (2013) Article DOI: 10.1016/j.bmc.2013.07.050 BindingDB Entry DOI: 10.7270/Q27082VV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM50441435 (CHEMBL2436265) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Curated by ChEMBL | Assay Description Inhibition of HO-1 in Sprague-Dawley rat spleen microsomal fractions assessed as carbon monoxide formation from methemalbumin after 10 mins by gas ch... | Bioorg Med Chem 21: 6788-95 (2013) Article DOI: 10.1016/j.bmc.2013.07.050 BindingDB Entry DOI: 10.7270/Q27082VV | |||||||||||
More data for this Ligand-Target Pair |