BDBM50441601 CHEMBL2437166

SMILES: Clc1ccc(OCC(=O)NNC(=S)NCCCn2ccnc2)cc1

InChI Key: InChIKey=SPWZQKFUKSMSJC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50441601 (CHEMBL2437166) Show SMILES Clc1ccc(OCC(=O)NNC(=S)NCCCn2ccnc2)cc1 Show InChI InChI=1S/C15H18ClN5O2S/c16-12-2-4-13(5-3-12)23-10-14(22)19-20-15(24)18-6-1-8-21-9-7-17-11-21/h2-5,7,9,11H,1,6,8,10H2,(H,19,22)(H2,18,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...				Eur J Med Chem 69: 244-61 (2013) Article DOI: 10.1016/j.ejmech.2013.08.027 BindingDB Entry DOI: 10.7270/Q2J967TM
					More data for this Ligand-Target Pair