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SMILES: O=C(COc1ccccc1)NNC(=S)NCc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=IZAIVBWEHZDHFE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441618   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
A disintegrin and metalloproteinase with thrombospondin motifs 5


(Homo sapiens (Human))		BDBM50441618
PNG
(CHEMBL2437187)
Show SMILES O=C(COc1ccccc1)NNC(=S)NCc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C22H21N3O2S/c26-21(16-27-20-9-5-2-6-10-20)24-25-22(28)23-15-17-11-13-19(14-12-17)18-7-3-1-4-8-18/h1-14H,15-16H2,(H,24,26)(H2,23,25,28)
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n/an/a 1.00E+4n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...

Eur J Med Chem 69: 244-61 (2013)


Article DOI: 10.1016/j.ejmech.2013.08.027
BindingDB Entry DOI: 10.7270/Q2J967TM
More data for this
Ligand-Target Pair