BDBM50442335 CHEMBL2442768

SMILES: CCOC(=O)c1cc(nc2c3cc[nH]c3ccc12)-c1ccc(OC)cc1

InChI Key: InChIKey=LIAUAUNLKQBFPC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50442335 (CHEMBL2442768) Show SMILES CCOC(=O)c1cc(nc2c3cc[nH]c3ccc12)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H18N2O3/c1-3-26-21(24)17-12-19(13-4-6-14(25-2)7-5-13)23-20-15(17)8-9-18-16(20)10-11-22-18/h4-12,22H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysis				J Med Chem 56: 7536-51 (2013) Article DOI: 10.1021/jm400377z BindingDB Entry DOI: 10.7270/Q2M046WV
					More data for this Ligand-Target Pair