BDBM50442651 CHEMBL2442011

SMILES: CCN(C1CCCC(N)C1)C(=O)c1ccccc1OCc1cccc(c1)C#N

InChI Key: InChIKey=UNOZLBRAPWGPEZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM50442651 (CHEMBL2442011) Show SMILES CCN(C1CCCC(N)C1)C(=O)c1ccccc1OCc1cccc(c1)C#N Show InChI InChI=1S/C23H27N3O2/c1-2-26(20-10-6-9-19(25)14-20)23(27)21-11-3-4-12-22(21)28-16-18-8-5-7-17(13-18)15-24/h3-5,7-8,11-13,19-20H,2,6,9-10,14,16,25H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	493	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assay				Bioorg Med Chem Lett 23: 6118-22 (2013) Article DOI: 10.1016/j.bmcl.2013.09.016 BindingDB Entry DOI: 10.7270/Q2125V4N
					More data for this Ligand-Target Pair