BDBM50442653 CHEMBL2442014

SMILES: CCN([C@H]1CCC[C@@H](N)C1)C(=O)c1ccccc1OCc1ccc(Cl)cc1

InChI Key: InChIKey=QXCUMEVOECPFAM-MOPGFXCFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM50442653 (CHEMBL2442014) Show SMILES CCN([C@H]1CCC[C@@H](N)C1)C(=O)c1ccccc1OCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H27ClN2O2/c1-2-25(19-7-5-6-18(24)14-19)22(26)20-8-3-4-9-21(20)27-15-16-10-12-17(23)13-11-16/h3-4,8-13,18-19H,2,5-7,14-15,24H2,1H3/t18-,19+/m1/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	254	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assay				Bioorg Med Chem Lett 23: 6118-22 (2013) Article DOI: 10.1016/j.bmcl.2013.09.016 BindingDB Entry DOI: 10.7270/Q2125V4N
					More data for this Ligand-Target Pair