BDBM50442662 CHEMBL2442022

SMILES: CCN([C@@H]1CCC[C@H](N)C1)C(=O)c1ccccc1OCc1ccccc1

InChI Key: InChIKey=FXOYOOYJFZTVMN-RBUKOAKNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM50442662 (CHEMBL2442022) Show SMILES CCN([C@@H]1CCC[C@H](N)C1)C(=O)c1ccccc1OCc1ccccc1 |r| Show InChI InChI=1S/C22H28N2O2/c1-2-24(19-12-8-11-18(23)15-19)22(25)20-13-6-7-14-21(20)26-16-17-9-4-3-5-10-17/h3-7,9-10,13-14,18-19H,2,8,11-12,15-16,23H2,1H3/t18-,19+/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assay				Bioorg Med Chem Lett 23: 6118-22 (2013) Article DOI: 10.1016/j.bmcl.2013.09.016 BindingDB Entry DOI: 10.7270/Q2125V4N
					More data for this Ligand-Target Pair