BDBM50442665 CHEMBL2442031

SMILES: CC(C)N([C@@H]1CCC[C@H](N)C1)C(=O)c1ccccc1OCc1ccccc1

InChI Key: InChIKey=HIMBSBQMUNDJAS-VQTJNVASSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM50442665 (CHEMBL2442031) Show SMILES CC(C)N([C@@H]1CCC[C@H](N)C1)C(=O)c1ccccc1OCc1ccccc1 |r| Show InChI InChI=1S/C23H30N2O2/c1-17(2)25(20-12-8-11-19(24)15-20)23(26)21-13-6-7-14-22(21)27-16-18-9-4-3-5-10-18/h3-7,9-10,13-14,17,19-20H,8,11-12,15-16,24H2,1-2H3/t19-,20+/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assay				Bioorg Med Chem Lett 23: 6118-22 (2013) Article DOI: 10.1016/j.bmcl.2013.09.016 BindingDB Entry DOI: 10.7270/Q2125V4N
					More data for this Ligand-Target Pair