BDBM50442668 CHEMBL2442037
SMILES: CCCN([C@@H]1CCC[C@H](N)C1)C(=O)c1ccccc1OCc1ccccc1
InChI Key: InChIKey=LLGUPACHQWNHJG-VQTJNVASSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human)) | BDBM50442668 (CHEMBL2442037) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assay | Bioorg Med Chem Lett 23: 6118-22 (2013) Article DOI: 10.1016/j.bmcl.2013.09.016 BindingDB Entry DOI: 10.7270/Q2125V4N | |||||||||||
More data for this Ligand-Target Pair |