BDBM50443205 CHEMBL3087037

SMILES: Cc1cc(ccn1)-c1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1

InChI Key: InChIKey=KUZUQSLQWYRGST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50443205 (CHEMBL3087037) Show SMILES Cc1cc(ccn1)-c1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1 Show InChI InChI=1S/C18H14Cl2N2O2S/c1-12-8-14(6-7-21-12)13-2-4-17(5-3-13)22-25(23,24)18-10-15(19)9-16(20)11-18/h2-11,22H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin) after 10 mins				Bioorg Med Chem Lett 23: 6447-54 (2013) Article DOI: 10.1016/j.bmcl.2013.09.041 BindingDB Entry DOI: 10.7270/Q2C53N9S
					More data for this Ligand-Target Pair