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SMILES: Clc1cc(Cl)cc(c1)S(=O)(=O)Nc1ccc(cc1)-c1ccco1

InChI Key: InChIKey=OGQIHASBDUUYTP-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443214   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 2D6


(Homo sapiens (Human))		BDBM50443214
PNG
(CHEMBL3087348)
Show SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)Nc1ccc(cc1)-c1ccco1
Show InChI InChI=1S/C16H11Cl2NO3S/c17-12-8-13(18)10-15(9-12)23(20,21)19-14-5-3-11(4-6-14)16-2-1-7-22-16/h1-10,19H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.70E+4n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6 (unknown origin) after 10 mins

Bioorg Med Chem Lett 23: 6447-54 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.041
BindingDB Entry DOI: 10.7270/Q2C53N9S
More data for this
Ligand-Target Pair