BDBM50443262 CHEMBL3087051

SMILES: Cc1cc(cc(C)c1O)N=Nc1cccc(c1)S(=O)(=O)Nc1ccccn1

InChI Key: InChIKey=AXNRGDLGWUFGKG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50443262 (CHEMBL3087051) Show SMILES Cc1cc(cc(C)c1O)N=Nc1cccc(c1)S(=O)(=O)Nc1ccccn1 |w:9.9| Show InChI InChI=1S/C19H18N4O3S/c1-13-10-16(11-14(2)19(13)24)22-21-15-6-5-7-17(12-15)27(25,26)23-18-8-3-4-9-20-18/h3-12,24H,1-2H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Displacement of fluorescein-labeled MS574 from recombinant human BRD4 BrD1 after 1 hr by fluorescence anisotropy assay				J Med Chem 56: 9251-64 (2013) Article DOI: 10.1021/jm401334s BindingDB Entry DOI: 10.7270/Q2ZW1NCF
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50443262 (CHEMBL3087051) Show SMILES Cc1cc(cc(C)c1O)N=Nc1cccc(c1)S(=O)(=O)Nc1ccccn1 |w:9.9| Show InChI InChI=1S/C19H18N4O3S/c1-13-10-16(11-14(2)19(13)24)22-21-15-6-5-7-17(12-15)27(25,26)23-18-8-3-4-9-20-18/h3-12,24H,1-2H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.04E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Displacement of fluorescein-labeled MS574 from recombinant human BRD4 BrD2 after 1 hr by fluorescence anisotropy assay				J Med Chem 56: 9251-64 (2013) Article DOI: 10.1021/jm401334s BindingDB Entry DOI: 10.7270/Q2ZW1NCF
					More data for this Ligand-Target Pair